Aspirin

Overview

A low-dose aspirin (75 mg/day) regimen has shown to combat multiple forms of cancer. Aspirin reduces the overall death from cancer by 20 per cent. This reduction continues for at least 20 years. The death rate reduction was even higher for older patients. The most effective salvage was in colon cancers of the ascending and transverse colon. Aspirin management for longer than five years appears to significantly reduce the risk of colorectal cancer.

The sooner one starts and the longer one takes aspirin, the better the results. Aspirin also reduces recurrence of adenomatous polyps of colon. Aspirin combats cancer by modulating or suppressing the pro-inflammatory enzyme cyclooxygenase -2, and "master-switch" protein complex nuclear factor-kappa B.

Separate studies have suggested a preventative effect for cancers of the esophagus, stomach, lung, breast, and ovaries. Also, some reduction in prostate cancer has been achieved.

COX-s facilitates cancer-formation by:

  • Triggering angiogenesis
  • Halting apoptosis
  • Inflicts DNA damage
  • Stimulates metastases
  • Suppresses immune surveillance

Activation of NF-kb launches a storm of cellular co-activators, signaling molecules, and transcription factors that drive tumor growth, angiogenesis and lethal metastases. Aspirin suppresses this activation.

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Management

  • Use low-dose of 75 mg/day
  • Zinc carnosine (zinc has gastro-protective affects and carnosine enhances these)
  • Cranberries (may help prevent esophageal cancer and thwart infection by helicobacter pylori)
  • Licorice extract (helps combat inflammation and block helicobacter pylori infection)
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