Systemic Lupus Erythematosus (S.L.E.)

Overview

In its most severe Systemic Lupus Erythematosus is a potentially fatal dysfunction of the auto-immune system. The body's multitude of immune agents mistakenly identifies its own tissues as the enemy. Discoid Lupus Erythematosus is a less serious form, and drug-induced LE (DILE) is transient.

S.L.E. Is primarily a disease of young women peaking between 15-20 years, but 40% may occur after the age of 60 years. It is an unpredictable disorder capable of long remissions and sudden unexplained flare-ups.

There are many possible causes of this disorder including genetic predisposition - chromosome 6 of HLA (human leukocyte area) - chromosome 1 (less commonly).Environmental factors may play a critical role in triggering S.L.E. These factors include:

  • Infections
  • Nutritional deficits
  • Stress

Cells that operate in this disorder:

  • Cells that focus on detecting and labeling antigens
  • Cells that choose the appropriate disease-fighting agent
  • Complement-system that regulates and clears up excess antibodies

If antibodies are in excess, and mediating substances are low, inflammation may be excessive and unchecked. In S.L.E., antibodies mis-identify as a foreign invader the body's own self-antigens.

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Symptoms

  • Photosensitivity
  • Mouth ulcers
  • Butterfly rashes
  • Discoid lesions
  • Joint inflammation
  • CNS-lesions
  • Kidneys
  • Lesions of heart and lungs
  • Blood test abnormalities

Affected Areas

  • Joints
  • Kidney
  • Heart (pericardium)
  • Lungs (pleura)
  • Skin
  • Mouth/Nose (ulcers)
  • C.N.S.
  • Blood (anemia and leukemia)
  • G.I. Tract
  • Vascular System (vasculitis)
  • Immune System (susceptible to infection)
  • Bones (osteoporosis)
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Management

Medical management will be determined for each specific case but the following are common management methods used at the Houston Wellness Clinic:

  • Steroids
  • Immuno-suppressive therapies
  • Intravenous immunoglobulins
  • Non-steroidal anti-inflammatory drugs (NSAIDS)
  • Antimalarial medication
  • Removal of drug-inducing S.L.E.
  • Thalidomide
  • Hormones
  • Testosterone Gastro-intestinal tract health - enzymes, probiotics, and liver support
  • Eliminate environment toxins
  • Mood elevations
  • Hydrogen peroxide therapy

You will want to avoid environmental triggers such as; aromatic amines (hair dyes), silicone/silica dust, alfalfa sprouts, hydrazines (found in mushroom and tobacco smoke), tatrazines (used as food preservatives in food dyes), stress

It's important to get ultraviolet light(both A and B) rest, exercise (aerobic exercises, build endurance and deter muscle atrophy and take nutritional aids) specific vitamins and minerals

Nutrition

  • E.F.A.'s (EPA/DHA)
  • Low saturated fats
  • Calorie, fat, and protein restriction
  • Antioxidants
  • DHEA

Overall, Dr. Allibone determines management options based on a highly individualized basis studying medical history, tests, lifestyle, etc. Using this specialized method, the clinic can put each patient on the path to optimal health.

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If we fill our hours with regrets of yesterday and with worries of tomorrow, we have no today in which to enjoy our existence. Seize the day, and take control of your health and life. How you are going to live those tomorrows will depend on how you act and choose today. - George Allibone M.D.